ATG4B Antikörper
Kurzübersicht für ATG4B Antikörper (ABIN7111893)
Target
Alle ATG4B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- ATG4B antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- ATG4 autophagy related 4 homolog B
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:500-1:2000 , IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
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Andere Bezeichnung
- ATG4B
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Hintergrund
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Synonyms: Cysteine protease ATG4B|AUT-like 1 cysteine endopeptidase|Autophagy-related cysteine endopeptidase 1 (Autophagin-1)|Autophagy-related protein 4 homolog B (HsAPG4B, hAPG4B)|ATG4B|APG4B|AUTL1|KIAA0943
Background: Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
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Molekulargewicht
- 44 kDa
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Gen-ID
- 23192
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UniProt
- Q9Y4P1
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Pathways
- Autophagie
Target
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